VP2 sequences of recent European 'very virulent' isolates of infectious bursal disease virus are closely related to each other but are distinct from those of 'classical' strains.

Abstract excerpt

Part of genomic segment A of five recent European 'very virulent' (VV) isolates of infectious bursal disease virus, encoding the major, conformational, protective epitope, have been reverse-transcribed, amplified and cloned. Sequence analysis of 582 bases of VP2 showed that the four U.K. isolates are closely related to each other, differing by no more than two bases, but are distinct from the 'classical' type 1...

Topics

• Amino Acid Sequence
• Animals
• Base Sequence
• Chickens
• Cloning, Molecular
• Genetic Variation
• Infectious bursal disease virus
• Molecular Sequence Data
• Viral Structural Proteins
• Virulence