Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structural differences between specific-locus mutations induced by different exposure regimes in mouse spermatogonial stem cells.

Mutation research - 1 Aug 1993

Russell L B, Rinchik E M

Abstract excerpt

It was first shown by W.L. Russell (1962), and confirmed by him and others, that a 24-h interval between dose fractions (but not shorter or longer ones) elevates the rate of radiation-induced spermatogonial specific-locus mutations to levels considerably above the linear extrapolation made from lower-dose results. We have now analyzed the nature of mutations induced either in previously undisturbed or in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Damage
Share to Mice
Share to Mutation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Spermatogonia

Share to Stem Cells

Source

Identifiers

PMID: 7688077
DOI: 10.1016/0027-5107(93)90084-s

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structural differences between specific-locus mutations induced by different exposure regimes in mouse spermatogonial stem cells.PMID 7688077Read ↗

Differential Response of Mouse Male Germ-Cell Stages to Radiation-Induced Specific-Locus and Dominant MutationsSemantic proximity Read ↗

The effect of dose rate on the frequency of specific-locus mutations induced in mouse spermatogonia is restricted to larger lesions; a retrospective analysis of historical data.Semantic proximity Read ↗

Effects of male germ-cell stage on the frequency, nature, and spectrum of induced specific-locus mutations in the mouse.Semantic proximity Read ↗

Ionizing radiation and genetic risks. II. Nature of radiation-induced mutations in experimental mammalian in vivo systems.Semantic proximity Read ↗

Mechanisms of mutation induction in germ cells of the mouse as assessed by the specific locus test.Semantic proximity Read ↗

Comparison of the genetic effects of equimolar doses of ENU and MNU: while the chemicals differ dramatically in their mutagenicity in stem-cell spermatogonia, both elicit very high mutation rates in differentiating spermatogonia.Semantic proximity Read ↗

The effect of the interval between dose applications on the observed specific-locus mutation rate in the mouse following fractionated treatments of spermatogonia with ethylnitrosourea.Semantic proximity Read ↗

Frequency and nature of specific-locus mutations induced in female mice by radiations and chemicals: a review.Semantic proximity Read ↗

Discovery of numerous clusters of spontaneous mutations in the specific-locus test in mice necessitates major increases in estimates of doubling doses.Semantic proximity Read ↗

Enhanced specific-locus mutation response of 101/H male mice to single, acute X-irradiation.Semantic proximity Read ↗

The mutagenic activity of ethylnitrosourea at low doses in spermatogonia of the mouse as assessed by the specific-locus test.Semantic proximity Read ↗

Gene and chromosome mutation after large fractionated or unfractionated radiation doses to mouse spermatogonia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.