Article
Immunological cross-reactivity of the C-terminal 42-kilodalton fragment of Plasmodium falciparum merozoite surface protein 1 expressed in baculovirus.
Infection and immunity - 1 Aug 1993
Hui G S, Hashiro C, Nikaido C, Case S E, Hashimoto A, Gibson H, Barr P J, Chang S P
Abstract excerpt
The roles of allelic and conserved epitopes in vaccine-induced immunity to the C-terminal 42-kDa fragment of the Plasmodium falciparum merozoite surface protein 1 (MSP1) were investigated. The C-terminal fragment of MSP1 was expressed as a baculovirus recombinant protein, BVp42. Rabbits were immunized with BVp42, and antibodies were tested for reactivity to MSP1s of the homologous and heterologous allelic forms,...
Topics
- Alleles
- Animals
- Antibodies, Protozoan
- Antigens, Protozoan
- Antigens, Surface
- B-Lymphocytes
- Baculoviridae
- Cross Reactions
- Epitopes
- Merozoite Surface Protein 1
- Peptide Fragments