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Article

Analysis of Antibodies Directed against Merozoite Surface Protein 1 of the Human Malaria ParasitePlasmodium falciparum

21 Jan 2006

Abstract excerpt

The 190-kDa merozoite surface protein 1 (MSP-1) of Plasmodium falciparum, an essential component in the parasite's life cycle, is a primary candidate for a malaria vaccine. Rabbit antibodies elicited by the heterologously produced MSP-1 processing products p83, p30, p38, and p42, derived from strain 3D7, were analyzed for the potential to inhibit in vitro erythrocyte invasion by the parasite and parasite growth....

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PMID: 16428781
DOI: 10.1128/iai.74.2.1313-1322.2006

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