Serum profiles of insulin-like growth factors and their binding proteins in adults with growth hormone receptor deficiency treated with insulin-like growth factor I.

doi:10.1111/j.1651-2227.1993.tb12838.x

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Article

Serum profiles of insulin-like growth factors and their binding proteins in adults with growth hormone receptor deficiency treated with insulin-like growth factor I.

Acta paediatrica (Oslo, Norway : 1992). Supplement - 1 Mar 1993

Fielder P J, Gargosky S E, Vaccarello M, Wilson K, Cohen P, Diamond F, Guevara-Aguirre J, Rosenbloom A L, Rosenfeld R G

Abstract excerpt

Six adult patients with growth hormone receptor deficiency (GHRD) (2 men, 4 women) with an identical defect in the growth hormone receptor (GHR) gene, were treated with recombinant human insulin-like growth factor I (IGF-I), 40 micrograms/kg s.c. twice daily, for 7 days. Serum concentrations of IGF peptide and IGF binding protein-3 (IGFBP-3) were measured by specific radioimmunoassays; serum IGFBPs were also...

Topics

Adult
Blotting, Western
Carrier Proteins
Chromatography, Gel
Chromatography, High Pressure Liquid
Female
Genetic Diseases, Inborn
Growth Disorders
Humans
Injections, Subcutaneous

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Insulin-Like Growth Factor Binding Protein 2

Insulin-Like Growth Factor Binding Proteins

Insulin-Like Growth Factor I

Insulin-Like Growth Factor II

Male

Molecular Weight

Phenotype

Radioimmunoassay

Source

Open in PubMed

Identifiers

PMID: 7687170
DOI: 10.1111/j.1651-2227.1993.tb12838.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7687170-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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