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Article

Sequences within the last intron function in RNA 3'-end formation in cultured cells.

Molecular and cellular biology - 1 Jun 1993

Nesic D, Cheng J, Maquat L E

Abstract excerpt

In cultured cells, little if any mRNA accumulates from an intronless version of the human gene for triosephosphate isomerase (TPI), a gene that normally contains six introns. By deleting introns either individually or in combinations, it was demonstrated by Northern (RNA) blot hybridization that...

Topics

Alleles
Animals
Base Sequence
Blotting, Northern
Humans
Introns
L Cells
Melanoma
Mice
Molecular Sequence Data
Oligodeoxyribonucleotides
Poly A
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

RNA

RNA Precursors

RNA, Messenger

Restriction Mapping

Source

Open in PubMed Open full text

Identifiers

PMID: 7684497
DOI: 10.1128/mcb.13.6.3359-3369.1993
PMCID: PMC359795

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7684497-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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