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Article

Sequences within the last intron function in RNA 3'-end formation in cultured cells.

Molecular and cellular biology - 1 Jun 1993

Nesic D, Cheng J, Maquat L E

Abstract excerpt

In cultured cells, little if any mRNA accumulates from an intronless version of the human gene for triosephosphate isomerase (TPI), a gene that normally contains six introns. By deleting introns either individually or in combinations, it was demonstrated by Northern (RNA) blot hybridization that while the deletion of a greater number of introns generally results in a lower level of product mRNA, not all introns...

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Identifiers

PMID: 7684497
DOI: 10.1128/mcb.13.6.3359-3369.1993
PMCID: PMC359795

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