Article
Intramembrane helix-helix interactions as the basis of inhibition of the colicin E1 ion channel by its immunity protein.
The Journal of biological chemistry - 15 May 1993
Zhang Y L, Cramer W A
Abstract excerpt
It had previously been hypothesized that the ability of a small number of immunity protein molecules in the cytoplasmic membrane to confer protection against the lethal effects of a channel-forming colicin involves a complex stabilized by electrostatic or polar interactions between immunity prote...
Topics
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- Colicins
- Escherichia coli
- Escherichia coli Proteins
- Genetic Vectors
- Genotype
- Ion Channels
- Models, Structural
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Plasmids
- Potassium
- Protein Structure, Secondary
- Recombinant Proteins
- Sequence Homology, Amino Acid