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Article

Energy-dependent immunity protein release during tol-dependent nuclease colicin translocation.

The Journal of biological chemistry - 10 Jul 2009

Vankemmelbeke Mireille, Zhang Ying, Moore Geoffrey R, Kleanthous Colin, Penfold Christopher N, James Richard

Abstract excerpt

Nuclease colicins bind their target receptor in the outer membrane of sensitive cells in the form of a high affinity complex with their cognate immunity proteins. Upon cell entry the immunity protein is lost from the complex by means that are poorly understood. We have developed a sensitive fluorescence assay that has enabled us to study the molecular requirements for immunity protein release. Nuclease colicins...

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Identifiers

PMID: 19458090
DOI: 10.1074/jbc.M806149200
PMCID: PMC2707214

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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