Article
Transmembrane alpha-helix interactions are required for the functional assembly of the Escherichia coli Tol complex.
Journal of molecular biology - 10 Feb 1995
Lazzaroni J C, Vianney A, Popot J L, Bénédetti H, Samatey F, Lazdunski C, Portalier R, Géli V
Abstract excerpt
TolQ, TolR and TolA are membrane proteins involved in maintaining the structure of Escherichia coli cell envelope. TolQ and TolR span the inner membrane with three and with one alpha-helical segments, respectively. The tolQ925 mutation (A177V), located in the third putative transmembrane helix of...
Topics
- Bacterial Proteins
- Colicins
- DNA Mutational Analysis
- Escherichia coli
- Escherichia coli Proteins
- Membrane Proteins
- Models, Biological
- Phenotype
- Protein Structure, Secondary
- Suppression, Genetic