Article
Contrasting molecular patterns of MHC class II alleles associated with the anti-Sm and anti-RNP precipitin autoantibodies in systemic lupus erythematosus.
Arthritis and rheumatism - 1 Jan 1993
Olsen M L, Arnett F C, Reveille J D
Abstract excerpt
OBJECTIVE: To find evidence of a potential genetic predisposition to the anti-Sm or anti-RNP precipitin autoantibody responses. METHODS: HLA-DR and DQ alleles determined by restriction fragment length polymorphism and/or oligotyping in 49 subjects with either anti-Sm alone or anti-RNP alone were compared with those in 139 race-matched normal control subjects and 59 race-matched lupus patients without anti-Sm and...
Topics
- Alleles
- Amino Acid Sequence
- Autoantibodies
- Autoantigens
- Base Sequence
- Epitopes
- HLA-DQ Antigens
- HLA-DR Antigens
- Histocompatibility Antigens Class II
- Humans
- Lupus Erythematosus, Systemic