Article
Interphase cytogenetics in paraffin sections of lung tumors by non-isotopic in situ hybridization. Mapping genotype/phenotype heterogeneity.
The American journal of pathology - 1 Jan 1993
Kim S Y, Lee J S, Ro J Y, Gay M L, Hong W K, Hittelman W N
Abstract excerpt
To better understand the relationship between specific chromosome changes found in human lung tumors and their phenotypic consequences at the tissue level, an in situ hybridization procedure was optimized for use on formalin-fixed paraffin-embedded tissue sections of human lung tumors. Pretreatme...
Topics
- Carcinoma, Non-Small-Cell Lung
- Chromosome Mapping
- Chromosomes, Human
- DNA Probes
- Genotype
- Humans
- In Situ Hybridization
- Interphase
- Lung Neoplasms
- Microtomy
- Paraffin Embedding
- Phenotype
- Protein Denaturation
- Staining and Labeling