Article
Analysis of phenotype and genotype of individual cells in neoplasms.
Cancer genetics and cytogenetics - 15 Jul 1993
Knuutila S, Larramendy M, Ruutu T, Paetau A, Heinonen K, Mahlamäki E
Abstract excerpt
The authors describe a combination technique enabling detection of in situ hybridization (ISH) signals from chromosome-specific probes in interphase or mitotic cells that still retain the alkaline phosphatase antialkaline phosphatase (APAAP) or Sudan black B (SBB) staining reactions (simultaneous detection) or have been first classified morphologically and then by APAAP or SBB. The technique can be used on cell...
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