Evidence of different complementation groups amongst human genetic disorders characterized by radiosensitivity.

doi:10.1016/0027-5107(93)90053-i

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Article

Evidence of different complementation groups amongst human genetic disorders characterized by radiosensitivity.

Mutation research - 1 Jan 1993

Chen P, Kidson C, Lavin M

Abstract excerpt

The genetic diversity of a clinically heterogeneous group of ionizing radiation-sensitive human mutants has been examined. In this group, the relationship between ataxia telangiectasia (A-T), Alzheimer's disease (AD) and Down's syndrome (DS) was studied, on the basis of their cellular radiosensit...

Topics

Alzheimer Disease
Ataxia Telangiectasia
Cell Fusion
Cell Line
Down Syndrome
Genetic Complementation Test
Humans
Phenotype
Radiation Tolerance

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