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Article

New HLA-DPB1 alleles generated by interallelic gene conversion detected by analysis of sperm.

Nature genetics - 1 Aug 1995

Zangenberg G, Huang M M, Arnheim N, Erlich H

Abstract excerpt

The rate at which allelic diversity at the HLA loci evolves has been the subject of considerable controversy. The patchwork pattern of sequence polymorphism within the second exon of the HLA class II loci, particularly in the DPB1 locus, may have been generated by segmental exchange (gene convers...

Topics

Alleles
Amino Acid Sequence
Artifacts
Base Sequence
DNA
Gene Conversion
Gene Frequency
HLA-DP Antigens
HLA-DP beta-Chains
Humans
Male
Molecular Sequence Data
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Spermatozoa

Source

Identifiers

PMID: 7670490
DOI: 10.1038/ng0895-407

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7670490-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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