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Article

The role of the Val353 residue in antagonist binding to rat CCK-B receptors.

Neuroreport - 19 Jun 1995

Malatynska E, Knapp R J, Stropova D, Varga E, Yamamura H I

Abstract excerpt

The Val353 residue of the rat cholecystokinin-B (CCK-B) receptor was mutated to Leu to test whether this residue is part of a binding site for antagonists having different chemical structures. The agonist radioligand [3H]SNF 8702 showed similar affinity for both wild-type and mutant receptors. Mutation of the CCK-B receptor reversed the order of affinities for the asperlicin derivatives from L-365,260 >...

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Source

Identifiers

PMID: 7669996
DOI: 10.1097/00001756-199506090-00024

Genes

CCK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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