Article
Role of a conserved lysine residue in the peripheral cannabinoid receptor (CB2): evidence for subtype specificity.
Molecular pharmacology - 1 Mar 1999
Tao Q, McAllister S D, Andreassi J, Nowell K W, Cabral G A, Hurst D P, Bachtel K, Ekman M C, Reggio P H, Abood M E
Abstract excerpt
The human cannabinoid receptors, central cannabinoid receptor (CB1) and peripheral cannabinoid receptor (CB2), share only 44% amino acid identity overall, yet most ligands do not discriminate between receptor subtypes. Site-directed mutagenesis was employed as a means of mapping the ligand recogn...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
