Article
STD1 (MSN3) interacts directly with the TATA-binding protein and modulates transcription of the SUC2 gene of Saccharomyces cerevisiae.
Nucleic acids research - 25 Aug 1995
Tillman T S, Ganster R W, Jiang R, Carlson M, Schmidt M C
Abstract excerpt
STD1 (MSN3) was isolated independently as a multicopy suppressor of mutations in the TATA-binding protein and in SNF4, suggesting that STD1 might couple the SNF1 kinase signaling pathway to the transcriptional machinery. We report here a direct physical interaction between STD1 and the TATA-binding protein (TBP), observed in vivo by the two-hybrid system and in vitro by binding studies. STD1 bound both native TBP...
Topics
- Base Sequence
- DNA Primers
- DNA-Binding Proteins
- Fungal Proteins
- Genes, Fungal
- Glutathione Transferase
- Intracellular Signaling Peptides and Proteins
- Molecular Sequence Data
- Phenotype
- Plasmids