Article
Human cytomegalovirus neutralizing antibody-resistant phenotype is associated with reduced expression of glycoprotein H.
Journal of virology - 1 Oct 1995
Li L, Coelingh K L, Britt W J
Abstract excerpt
We have characterized a neutralizing antibody-resistant mutant human cytomegalovirus (HCMV) obtained from a patient treated with a human monoclonal antiglycoprotein H (gH; unique long region 75) antibody. This virus exhibited resistance to several different neutralizing anti-gH murine monoclonal antibodies (MAbs), as well as to a polyvalent anti-gH serum. The resistant phenotype was unstable and could be...
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