Article
Glycoprotein N of human cytomegalovirus protects the virus from neutralizing antibodies.
PLoS pathogens - 1 Jan 2012
Kropff Barbara, Burkhardt Christiane, Schott Juliane, Nentwich Jens, Fisch Tanja, Britt William, Mach Michael
Abstract excerpt
Herpes viruses persist in the infected host and are transmitted between hosts in the presence of a fully functional humoral immune response, suggesting that they can evade neutralization by antiviral antibodies. Human cytomegalovirus (HCMV) encodes a number of polymorphic highly glycosylated virion glycoproteins (g), including the essential envelope glycoprotein, gN. We have tested the hypothesis that...
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