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Article

Clinical implications of p53: effect on prognosis, tumor progression and chemotherapy response.

Seminars in cancer biology - 1 Jan 1998

Peller S

Abstract excerpt

The p53 tumor suppressor gene is frequently mutated in most human malignancies. These mutations have been associated with clinical outcome for various cancer types. Since this gene's main function is to guard the integrity of the genome, its clinical relevance, i.e. its role in carcinogenesis and chemotherapy-drug resistance, have been extensively studied. These data and the p53 protein as a potential target for...

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Identifiers

PMID: 10101803
DOI: 10.1006/scbi.1998.0100

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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