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Article

Modification of the acoustic startle response in hearing-impaired C57BL/6J mice: prepulse augmentation and prolongation of prepulse inhibition.

Behavioral neuroscience - 1 Jun 1995

Willott J F, Carlson S

Abstract excerpt

Modification of acoustic startle amplitude by a 10-ms tone prepulse (S1) was evaluated as a function of the interstimulus interval (ISI) between the onset of S1 and the onset of the startle-evoking stimulus (S2). Subjects were normal-hearing 1-month-old C57BL/6J (C57) mice and CBA/CaJ mice and 5-month-old C57 mice with high-frequency hearing loss. With a 2-ms ISI, 5-month-old C57 mice (but not the normal-hearing...

Topics

Animals
Arousal
Auditory Threshold
Female
Genotype
Male
Mice
Mice, Inbred C57BL
Mice, Inbred CBA
Neural Inhibition
Psychoacoustics
Reflex, Startle

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Identifiers

PMID: 7662150
DOI: 10.1037//0735-7044.109.3.396

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7662150-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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