Article

Age-Related Central Gain with Degraded Neural Synchrony in the Auditory Brainstem of Mice and Humans

2022-02-25

Abstract excerpt

Aging is associated with auditory nerve (AN) functional deficits and decreased inhibition in the central auditory system, amplifying central responses in a process known as central gain. Although central gain enhances response amplitudes, central gain may not restore disrupted response timing. In this translational study, we measured responses from the AN and auditory midbrain in younger and older mice and humans....

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Literature Corpus work: 24bca07f-f547-5620-9152-c4e880787f86
DOI: 10.1101/2022.02.23.481643

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