Experimental evaluation of the ribonuclease protection assay method for the assessment of genetic heterogeneity in populations of RNA viruses.

doi:10.1007/BF01322664

Back to search

Article

Experimental evaluation of the ribonuclease protection assay method for the assessment of genetic heterogeneity in populations of RNA viruses.

Archives of virology - 1 Jan 1995

Aranda M A, Fraile A, Garcia-Arenal F, Malpica J M

Abstract excerpt

The ribonuclease (RNase) protection assay (RPA) was evaluated as a method to estimate genetic distances among sequence variants of RNA viruses. The patterns of fragments generated, under different RPA conditions, by three sets of RNA sequence variants of known nucleotide sequence, were analyzed....

Topics

Cucumovirus
Genetic Heterogeneity
Genetic Variation
Molecular Sequence Data
Nucleic Acid Heteroduplexes
RNA, Viral
Ribonuclease, Pancreatic
Tobacco Mosaic Virus

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.