Article
Reciprocal stimulation of GTP hydrolysis by two directly interacting GTPases.
Science (New York, N.Y.) - 8 Sept 1995
Powers T, Walter P
Abstract excerpt
The Escherichia coli guanosine triphosphate (GTP)-binding proteins Ffh and FtsY have been proposed to catalyze the cotranslational targeting of proteins to the bacterial plasma membrane. A mutation was introduced into the GTP-binding domain of FtsY that altered its nucleotide specificity from GTP to xanthosine triphosphate (XTP). The mutant FtsY protein stimulated GTP hydrolysis by a ribonucleoprotein consisting...
Topics
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- Enzyme Activation
- Escherichia coli Proteins
- GTP Phosphohydrolases
- GTP-Binding Proteins
- Guanosine Triphosphate
- Hydrolysis
- Molecular Sequence Data
- Mutation