Article
High frequency of chromosome 9p allelic loss and CDKN2 tumor suppressor gene alterations in squamous cell carcinoma of the bladder.
Journal of the National Cancer Institute - 20 Sept 1995
Gonzalez-Zulueta M, Shibata A, Ohneseit P F, Spruck C H, Busch C, Shamaa M, El-Baz M, Nichols P W, Gonzalgo M L, Elbaz M [corrected to El-Baz M ]
Abstract excerpt
BACKGROUND: In the Western Hemisphere, 90% of bladder cancers are transitional cell carcinomas, while only 7% are classified as squamous cell carcinomas. In contrast, in Egypt and regions of the Middle East and Africa, where infection by the trematode Schistosoma haematobium is endemic, squamous...
Topics
- Alleles
- Base Sequence
- Carcinoma, Squamous Cell
- Carcinoma, Transitional Cell
- Chromosome Deletion
- Chromosomes, Human, Pair 17
- Chromosomes, Human, Pair 9
- Egypt
- Genes, Tumor Suppressor
- Genes, p53
- Homozygote
- Humans
- Immunohistochemistry