Article
A simple molecular assay for the C1166 variant of the angiotensin II type 1 receptor gene.
Biochemical and biophysical research communications - 15 Aug 1995
Hingorani A D, Brown M J
Abstract excerpt
Studies of human polygenic diseases require the genotyping of polymorphic markers from large numbers of subjects. The rapid detection of the insertion (I)/deletion(D) polymorphism of the angiotensin converting enzyme (ACE) gene by the polymerase chain reaction (PCR) has facilitated the study of this locus in a a number of cardiovascular diseases, but not all gene polymorphisms are as easily detected. We describe...
Topics
- Base Sequence
- Humans
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Receptors, Angiotensin