Article
Mutations sensitizing yeast cells to the start inhibitor nalidixic acid.
Yeast (Chichester, England) - 1 May 1995
Prendergast J A, Singer R A, Rowley N, Rowley A, Johnston G C, Danos M, Kennedy B, Gaber R F
Abstract excerpt
The regulatory step Start in the cell cycle of the budding yeast Saccharomyces cerevisiae is inhibited by nalidixic acid (Nal). To study this inhibition, mutations were identified that alter the sensitivity of yeast cells to Nal. Nal-sensitive mutations were sought because the inhibitory effects of Nal on wild-type cells are only transient, and wild-type cells naturally become refractory to Nal. Three...
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