Article
The Saccharomyces cerevisiae mutation elm4-1 facilitates pseudohyphal differentiation and interacts with a deficiency in phosphoribosylpyrophosphate synthase activity to cause constitutive pseudohyphal growth.
Molecular and cellular biology - 1 Jul 1994
Blacketer M J, Madaule P, Myers A M
Abstract excerpt
Saccharomyces cerevisiae mutant E124 was selected in a visual screen based on elongated cell shape. Genetic analysis showed that E124 contains two separate mutations, pps1-1 and elm4-1, each causing a distinct phenotype inherited as a single-gene trait. In rich medium, pps1-1 by itself causes inc...
Topics
- Amino Acid Sequence
- DNA, Fungal
- Gene Deletion
- Genes, Fungal
- Genomic Library
- Humans
- Kinetics
- Molecular Sequence Data
- Mutagenesis
- Phenotype
- Restriction Mapping
- Ribose-Phosphate Pyrophosphokinase
- Saccharomyces cerevisiae
- Sequence Homology, Amino Acid