Article

High-Throughput Screening by Flow Cytometry Identifies Reduced Expression of CD48 As a Universal Characteristic of T-ALL and a Suitable Target for Minimal Residual Disease (MRD) Detection

2011-11-18

Abstract excerpt

Abstract Abstract 2547 The flow cytometric detection of minimal residual disease (MRD) relies on the differential expression of antigens between normal and leukemic cell populations of similar lineage. In T-cell lymphoblastic leukemia (T-ALL), the principal normal populations from which leukemic blasts must be distinguished are mature T cells and NK cells, as immature T cells are not normally present in peripheral...

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Acute Lymphoblastic Leukemia research

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Literature Corpus work: 20f4460a-dea0-5d35-b93d-ce949e821168
DOI: 10.1182/blood.v118.21.2547.2547

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