Article
γδ T Cells for Leukemia Immunotherapy: New and Expanding Trends.
Frontiers in immunology - 1 Jan 2021
Barros Mateus de Souza, de Araújo Nilberto Dias, Magalhães-Gama Fábio, Pereira Ribeiro Thaís Lohana, Alves Hanna Fabíola Silva, Tarragô Andréa Monteiro, Malheiro Adriana, Costa Allyson Guimarães
Abstract excerpt
Recently, many discoveries have elucidated the cellular and molecular diversity in the leukemic microenvironment and improved our knowledge regarding their complex nature. This has allowed the development of new therapeutic strategies against leukemia. Advances in biotechnology and the current understanding of T cell-engineering have led to new approaches in this fight, thus improving cell-mediated immune...
Topics
- Animals
- Antineoplastic Agents, Immunological
- Cell Proliferation
- Humans
- Immune Checkpoint Inhibitors
- Immunotherapy, Adoptive
- Intraepithelial Lymphocytes
- Leukemia
- Lymphocyte Activation
- Lymphocytes, Tumor-Infiltrating