Article
No association of TAP1 and TAP2 genes polymorphism with risk of cervical cancer in north Indian population.
Journal of assisted reproduction and genetics - 1 Apr 2009
Kordi Tamandani Dor Mohammad, Sobti Ranbir Chander, Shekari Mohammad, Husseini Seyd Ali, Suri Vanita
Abstract excerpt
BACKGROUND: Transporter associated with antigen processing (TAP), a member of the ATP-binding cassette transporter super family, is composed of two integral membrane proteins, TAP-1 and TAP-2. The TAP gene product is involved in the processing of endogenous peptides that bind to MHC class I molecules. Mutations and/or polymorphism within these genes could alter the efficacy of the immune response which might be...
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