Article
Construction of murine coronavirus mutants containing interspecies chimeric nucleocapsid proteins.
Journal of virology - 1 Sept 1995
Peng D, Koetzner C A, McMahon T, Zhu Y, Masters P S
Abstract excerpt
Targeted RNA recombination was used to construct mouse hepatitis virus (MHV) mutants containing chimeric nucleocapsid (N) protein genes in which segments of the bovine coronavirus N gene were substituted in place of their corresponding MHV sequences. This defined portions of the two N proteins that, despite evolutionary divergence, have remained functionally equivalent. These regions included most of the...
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