Article
Construction of murine coronavirus mutants containing interspecies chimeric nucleocapsid proteins.
Journal of virology - 1 Sept 1995
Peng D, Koetzner C A, McMahon T, Zhu Y, Masters P S
Abstract excerpt
Targeted RNA recombination was used to construct mouse hepatitis virus (MHV) mutants containing chimeric nucleocapsid (N) protein genes in which segments of the bovine coronavirus N gene were substituted in place of their corresponding MHV sequences. This defined portions of the two N proteins th...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Biological Evolution
- Capsid
- Cell Line
- Coronavirus, Bovine
- Crossing Over, Genetic
- DNA, Ribosomal
- Genetic Variation
- Mice
- Molecular Sequence Data
- Murine hepatitis virus
- Mutagenesis
- Oligodeoxyribonucleotides
- Plasmids
- RNA, Viral
- Recombinant Fusion Proteins