Optimization of targeted RNA recombination and mapping of a novel nucleocapsid gene mutation in the coronavirus mouse hepatitis virus.

doi:10.1128/JVI.68.1.328-337.1994

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Article

Optimization of targeted RNA recombination and mapping of a novel nucleocapsid gene mutation in the coronavirus mouse hepatitis virus.

Journal of virology - 1 Jan 1994

Masters P S, Koetzner C A, Kerr C A, Heo Y

Abstract excerpt

We have recently described a method of introducing site-specific mutations into the genome of the coronavirus mouse hepatitis virus (MHV) by RNA recombination between cotransfected genomic RNA and a synthetic subgenomic mRNA (C. A. Koetzner, M. M. Parker, C. S. Ricard, L. S. Sturman, and P. S. Ma...

Topics

Amino Acid Sequence
Animals
Base Sequence
Capsid
Chromosome Mapping
Clone Cells
Defective Viruses
Genes, Viral
Mice
Molecular Sequence Data
Murine hepatitis virus
Mutation
RNA, Viral
Recombination, Genetic
Sequence Analysis, DNA
Sequence Homology, Amino Acid
Viral Core Proteins
Viral Matrix Proteins

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Identifiers

PMID: 8254744
DOI: 10.1128/JVI.68.1.328-337.1994
PMCID: PMC236292

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8254744-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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