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Article

Escherichia coli DNA polymerase III tau- and gamma-subunit conserved residues required for activity in vivo and in vitro.

Journal of bacteriology - 1 Nov 2000

Walker J R, Hervas C, Ross J D, Blinkova A, Walbridge M J, Pumarega E J, Park M O, Neely H R

Abstract excerpt

The Escherichia coli DNA polymerase III tau and gamma subunits are single-strand DNA-dependent ATPases (the latter requires the delta and delta' subunits for significant ATPase activity) involved in loading processivity clamp beta. They are homologous to clamp-loading proteins of many organisms from phages to humans. Alignment of 27 prokaryotic tau/gamma homologs and 1 eukaryotic tau/gamma homolog has refined the...

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Identifiers

PMID: 11029431
DOI: 10.1128/JB.182.21.6106-6113.2000
PMCID: PMC94745

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SRC

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Source receipt: pubmed, retrieved 7 Sept 2026.

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