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Article

Polymorphisms of GSTM1 and GSTT1, sun exposure and the risk of melanoma: a case-control study.

Acta dermato-venereologica - 1 May 2011

Fortes Cristina, Mastroeni Simona, Boffetta Paolo, Innocenzi Luciano, Antonelli Gianluca, Giovinazzo Raffaella, Anzidei Patrizia, Melchi Franco, D' Atri Stefania, Pasquini Paolo, Venanzetti Frederica

Abstract excerpt

Glutathione S-transferases (GSTs) are a family of enzymes that are known to play an important role in cellular protection against oxidative stress, including the oxidative stress caused by ultraviolet radiation. This study focused on the possible involvement of GSTM1 and GSTT1 polymorphisms in risk modulation of cutaneous melanoma. Within a case-control study, the presence of the null polymorphism at GSTM1 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21461548
DOI: 10.2340/00015555-1078

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Polymorphisms of GSTM1 and GSTT1, sun exposure and the risk of melanoma: a case-control study.PMID 21461548Read ↗

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Protective effect of copy number polymorphism of glutathione S-transferase T1 gene on melanoma risk in presence of CDKN2A mutations, MC1R variants and host-related phenotypes.Semantic proximity Read ↗

The GSTM1 null genotype confers an increased risk for solar keratosis development in an Australian Caucasian population.Semantic proximity Read ↗

Association of the glutathione s-transferase m1, t1 polymorphisms with cancer: evidence from a meta-analysis.Semantic proximity Read ↗

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Glutathione S-transferase GSTM1 phenotypes and protection against cutaneous tumours.Semantic proximity Read ↗

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