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Article

The effects of<i>Plasmodium falciparum</i>malaria on immune control of B lymphocytes in Gambian children

1 May 1990

Abstract excerpt

Children living in hyperendemic malarious regions have high immunoglobulin levels and an increased frequency of Burkitt's lymphoma. In a study of Gambian children which endeavours to explain these findings we showed that acute P. falciparum malaria caused spontaneous activation and growth of their B lymphocytes in vitro. A high proportion of these cells contained Epstein-Barr nuclear antigen (EBNA). In ancillary...

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PMID: 1972671
DOI: 10.1111/j.1365-2249.1990.tb05236.x

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