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Article

Novel function of Rad27 (FEN-1) in restricting short-sequence recombination.

Molecular and cellular biology - 1 Apr 2001

Negritto M C, Qiu J, Ratay D O, Shen B, Bailis A M

Abstract excerpt

Saccharomyces cerevisiae mutants lacking the structure-specific nuclease Rad27 display an enhancement in recombination that increases as sequence length decreases, suggesting that Rad27 preferentially restricts recombination between short sequences. Since wild-type alleles of both RAD27 and its human homologue FEN1 complement the elevated short-sequence recombination (SSR) phenotype of a rad27-null mutant, this...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11259584
DOI: 10.1128/MCB.21.7.2349-2358.2001
PMCID: PMC86868

Genes

FEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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