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Article

Activation of Dictyostelium myosin light chain kinase A by phosphorylation of Thr166.

The EMBO journal - 15 Nov 1996

Smith J L, Silveira L A, Spudich J A

Abstract excerpt

Phosphorylation of the regulatory light chain is an important mechanism for the activation of myosin in non-muscle cells. Unlike most myosin light chain kinases (MLCKs), MLCK-A from Dictyostelium is not activated by Ca2+/calmodulin. Autophosphorylation increases activity, but only to a low level, suggesting that there is an additional activation mechanism. Here, we show that MLCK-A is autophosphorylated on...

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Identifiers

PMID: 8947030
PMCID: PMC452429

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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