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Article

N-terminal α7 deletion of the proteasome 20S core particle substitutes for yeast PI31 function.

Molecular and cellular biology - 1 Jan 2015

Yashiroda Hideki, Toda Yousuke, Otsu Saori, Takagi Kenji, Mizushima Tsunehiro, Murata Shigeo

Abstract excerpt

The proteasome core particle (CP) is a conserved protease complex that is formed by the stacking of two outer α-rings and two inner β-rings. The α-ring is a heteroheptameric ring of subunits α1 to α7 and acts as a gate that restricts entry of substrate proteins into the catalytic cavity formed by the two abutting β-rings. The 31-kDa proteasome inhibitor (PI31) was originally identified as a protein that binds to...

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Identifiers

PMID: 25332237
DOI: 10.1128/MCB.00582-14
PMCID: PMC4295373

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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