Article
Genetic analyses of tattered, an X-linked dominant, developmental mouse mutation.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 1995
Merrell K, Gonzales J C, Wells S, Calame K, Herman G E
Abstract excerpt
Tattered (Td) is an X-linked dominant mouse mutation that causes prenatal lethality in affected males. To map the locus, we analyzed 199 normal male and affected female progeny from a backcross of Td and Mus castaneus. Pedigree analysis of these animals suggests a gene order of cen-DXWas70-(Td, DXMit26, Gata1, Tcfe3)-(Cybb, Otc)-tel, where Tcfe3 is a transcription factor homologous to a gene involved in the...
Topics
- Animals
- Blotting, Western
- Chromosome Mapping
- Crosses, Genetic
- Female
- Flow Cytometry
- Genes, Lethal
- Genetic Linkage
- Haplotypes
- Heterozygote
- Male
