Genetic and molecular evidence of an X-chromosome deletion spanning the tabby (Ta) and testicular feminization (Tfm) loci in the mouse.

doi:10.1159/000133070

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Article

Genetic and molecular evidence of an X-chromosome deletion spanning the tabby (Ta) and testicular feminization (Tfm) loci in the mouse.

Cytogenetics and cell genetics - 1 Jan 1991

Cattanach B M, Rasberry C, Evans E P, Dandolo L, Simmler M C, Avner P

Abstract excerpt

A new radiation-induced mutation in the mouse, tabby-25H (Ta25H), has proved to be a deletion which spans both the tabby and testicular feminization (Tfm) loci on the X chromosome. The Ta phenotype closely resembles that of the original TaFa mutation in both the heterozygous and hemizygous condit...

Topics

Androgen-Insensitivity Syndrome
Animals
Chromosome Deletion
Chromosome Mapping
DNA Probes
Female
Genes
Genetic Linkage
Male
Mice
Phenotype
X Chromosome

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