Apolipoprotein E alleles and brain vascular pathology in Alzheimer's disease.

doi:10.1111/j.1749-6632.1996.tb34430.x

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Article

Apolipoprotein E alleles and brain vascular pathology in Alzheimer's disease.

Annals of the New York Academy of Sciences - 17 Jan 1996

Kalaria R N, Cohen D L, Premkumar D R

Abstract excerpt

The presence of apolipoprotein E (ApoE)-E4 allele has been implicated as a risk factor for Alzheimer's disease (AD). We examined the occurrence of ApoE 4 alleles in AD associated with cerebral amyloid angiopathy and other vascular lesions. We found significantly high frequency of the ApoE 4 allel...

Topics

Aged
Aged, 80 and over
Alleles
Alzheimer Disease
Apolipoproteins E
Cerebral Amyloid Angiopathy
Cerebrovascular Disorders
Humans
Immunohistochemistry
Middle Aged

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