Article
Association between HLA-DQB1*03:01 and Bullous pemphigoid in Iranian patients.
Iranian journal of immunology : IJI - 1 Mar 2013
Esmaili Nafiseh, Mortazavi Hossein, Chams-Davatchi Cheyda, Daneshpazhooh Maryam, Damavandi Maede Rayati, Aryanian Zeinab, Amirzargar Ali Akbar
Abstract excerpt
BACKGROUND: A common Human Leukocyte Antigen (HLA) class II allele, DQβ1*03:01, seems to be associated with Bullous pemphigoid (BP) in Caucasians whereas previous studies in other ethnic groups showed other HLA class II alleles as genetic predisposing factors for BP. OBJECTIVE: To investigate the association of HLA class II alleles and haplotypes with BP in Iranian population. METHODS: Fifty patients with Bullous...
Topics
- Ethnicity
- Female
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- HLA-DQ beta-Chains
- Haplotypes
- Histocompatibility Testing
- Humans
- Iran
- Male
- Mutation
- Pemphigoid, Bullous
- Polymorphism, Genetic