Article
HLA-DRB1/DQB1 susceptibility for autoimmune polyglandular syndrome type II and III in south of Tunisia.
Annales d'endocrinologie - 1 Jun 2011
Fourati H, Mahfoudh N, Abida O, Kammoun A, Mnif F, Haddouk S, Ben Ayed M, Ben Hadj Hmida Y, Rekik N, Abid M, Makni H, Masmoudi H
Abstract excerpt
OBJECTIVES: The aim of our study was to investigate the association of HLA-DRB1 and HLA-DQB1 alleles with autoimmune polyglandular syndromes (APS) type II and III in a southern Tunisian population. PATIENTS AND METHODS: Sixty-two unrelated patients with APSII (n=20) and APSIII (n=42) and 146 healthy controls were genotyped for HLA class II alleles (DRB1*, DQB1*) by PCR-SSP technique. RESULTS: An increased...
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