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Article

Mitochondrial diabetes mellitus--glucose-induced signaling defects and beta-cell loss.

Muscle & nerve. Supplement - 1 Jan 1995

Oka Y, Katagiri H, Ishihara H, Asano T, Kikuchi M, Kobayashi T

Abstract excerpt

Japanese diabetic patients whose mothers were also diabetic were screened, using peripheral leukocytes, for an A to G transition at nucleotide pair 3243 of the mitochondrial gene, a tRNA(Leu)(UUR) mutation. This mutation was identified in four pedigrees from among 300 unrelated patients. Diabetes mellitus cosegretated with the mutation, except in 1 young subject, and was maternally inherited. Long-term follow-up...

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Identifiers

PMID: 7603514
DOI: 10.1002/mus.880181426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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