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Mitochondrial Diabetes

1 Feb 2004

Abstract excerpt

Mutations in mitochondrial DNA (mtDNA) associate with various disease states. A few mtDNA mutations strongly associate with diabetes, with the most common mutation being the A3243G mutation in the mitochondrial DNA-encoded tRNA(Leu,UUR) gene. This article describes clinical characteristics of mitochondrial diabetes and its molecular diagnosis. Furthermore, it outlines recent developments in the pathophysiological...

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Identifiers

PMID: 14749274
DOI: 10.2337/diabetes.53.2007.s103

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