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Article

Diabetes mellitus carrying a mutation in the mitochondrial tRNA(Leu(UUR)) gene.

Diabetologia - 1 Feb 1995

Kishimoto M, Hashiramoto M, Araki S, Ishida Y, Kazumi T, Kanda E, Kasuga M

Abstract excerpt

We screened 214 Japanese NIDDM (non-insulin-dependent) diabetic patients with a family history of diabetes for mutations in the mitochondrial tRNA(Leu(UUR)) gene using polymerase chain reaction-restriction fragment length polymorphism and direct sequencing. Six patients were identified as having...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Base Sequence
C-Peptide
Case-Control Studies
Diabetes Mellitus, Type 2
Female
Genetic Variation
Glucagon
Humans
MELAS Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Mitochondria

Molecular Sequence Data

Pedigree

Source

Identifiers

PMID: 7713314
DOI: 10.1007/BF00400094

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7713314-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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