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Glucocorticoid Regulation of Bone Sialoprotein (BSP) Gene Expression

1 May 1995

Abstract excerpt

Glucocorticoids modulate the development and growth of many organs through interactions with a specific intracellular receptor (glucocorticoid receptor) that regulates gene transcription through a cognate element, the glucocorticoid response element (GRE), in the promoter of target genes. In bone formation glucocorticoids stimulate osteoblast differentiation and the formation of bone matrix. Recent studies have...

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PMID: 7601099
DOI: 10.1111/j.1432-1033.1995.0183i.x

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