Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Insulin-like growth factor-II regulates bone sialoprotein gene transcription.

Odontology - 1 Sept 2016

Choe Jin, Sasaki Yoko, Zhou Liming, Takai Hideki, Nakayama Yohei, Ogata Yorimasa

Abstract excerpt

Insulin-like growth factor-I and -II (IGF-I and IGF-II) have been found in bone extracts of several different species, and IGF-II is the most abundant growth factor stored in bone. Bone sialoprotein (BSP) is a noncollagenous extracellular matrix glycoprotein associated with mineralized connective tissues. In this study, we have investigated the regulation of BSP transcription by IGF-II in rat osteoblast-like...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclic AMP Response Element-Binding Protein
Share to Fibroblast Growth Factor 2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Homeodomain Proteins

Share to Insulin-Like Growth Factor II

Share to Osteoblasts

Share to Phosphoinositide-3 Kinase Inhibitors

Share to Protein-Tyrosine Kinases

Share to Transcription, Genetic

Source

Identifiers

PMID: 25895664
DOI: 10.1007/s10266-015-0205-6

Genes

FGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insulin-like growth factor-II regulates bone sialoprotein gene transcription.PMID 25895664Read ↗

Insulin-like growth factor-I increases bone sialoprotein (BSP) expression through fibroblast growth factor-2 response element and homeodomain protein-binding site in the proximal promoter of the BSP gene.Semantic proximity Read ↗

Effects of interleukin-11 on the expression of human bone sialoprotein gene.Semantic proximity Read ↗

CREB-1 and AP-1 transcription factors JunD and Fra-2 regulate bone sialoprotein gene expression in human breast cancer cells.Semantic proximity Read ↗

Prostaglandin E2 Stimulates Bone Sialoprotein (BSP) Expression through cAMP and Fibroblast Growth Factor 2 Response Elements in the Proximal Promoter of the Rat BSP GeneSemantic proximity Read ↗

Glucocorticoid Regulation of Bone Sialoprotein (BSP) Gene ExpressionSemantic proximity Read ↗

Transforming growth factor-β1 regulation of bone sialoprotein gene transcription: Identification of a TGF-β activation element in the rat BSP gene promoterSemantic proximity Read ↗

Cloning of a 2.5 kb murine bone sialoprotein promoter fragment and functional analysis of putative Osf2 binding sites.Semantic proximity Read ↗

Butyric acid stimulates bone sialoprotein gene transcription.Semantic proximity Read ↗

Cooperative Interactions between RUNX2 and Homeodomain Protein-binding Sites Are Critical for the Osteoblast-specific Expression of the Bone Sialoprotein GeneSemantic proximity Read ↗

Identification of a Homeodomain Binding Element in the Bone Sialoprotein Gene Promoter That Is Required for Its Osteoblast-selective ExpressionSemantic proximity Read ↗

Identification of an osteogenic protein-1 (bone morphogenetic protein-7)-responsive element in the promoter of the rat insulin-like growth factor-binding protein-5 gene.Semantic proximity Read ↗

Response of bipotential human marrow stromal cells to insulin-like growth factors: effect on binding protein production, proliferation, and commitment to osteoblasts and adipocytes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.