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Article

Effects of interleukin-11 on the expression of human bone sialoprotein gene.

Journal of bone and mineral metabolism - 1 Mar 2015

Matsumura Hiroyoshi, Nakayama Yohei, Takai Hideki, Ogata Yorimasa

Abstract excerpt

Interleukin-11 (IL-11) is a bone marrow stromal fibroblast-derived cytokine with a wide spectrum of activities in different biological systems. IL-11 and IL-6 are two cytokines known to rely on osteoblast-osteoclast communication for their effects on osteoclast differentiation. Bone sialoprotein (BSP) is a mineralized connective tissue-specific protein expressed in differentiated osteoblasts, odontoblasts, and...

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PMID: 24633490
DOI: 10.1007/s00774-014-0576-8

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